Outer Envelope of Virulent Treponema pallidum
نویسندگان
چکیده
منابع مشابه
Molecular cloning of Treponema pallidum outer envelope fibronectin binding proteins , P 1 and P 2 KENNETH
Phages directing the synthesis of Treponema pallidum fibronectin binding adhesin proteins, P1 and P2,' were isolated from an EMBL-3 bacteriophage lambda library of T pallidum deoxyribonucleic acid (DNA). The recombinant phages were identified using antisera generated to treponemal proteins purified in fibronectin-Sepharose. Recombinant P1 and P2 proteins possessed the same relative molecular we...
متن کاملEffect of gentamicin sulphate on avirulent and virulent Treponema pallidum.
The bactericidal activity of the aminoglycoside gentamicin has been demonstrated against a broad spectrum of bacteria (Jackson and Finland, 1969). This spectrum included Neisseria gonorrhoeae (Waitz and Weinstein, 1969); however, before gentamicin is used for the treatment of gonorrhoea, its effect on Treponema pallidum should be investigated to determine whether it can delay or mask the develo...
متن کاملMolecular specificities of monoclonal antibodies directed against virulent Treponema pallidum.
Radioimmunoprecipitation (RIP) and Western blot analyses with specific anti-Treponema pallidum subsp. pallidum monoclonal antibodies were used to identify antigens with apparent masses of 102, 84, 54, 53, 52, 47, 32, 29, and 24 kilodaltons (kDa). Cross-reactivity of these antibodies with T. pallidum subsp. pertenue antigens and lack of cross-reactivity with T. phagedenis biotype Reiter, T. vinc...
متن کاملParasitism by virulent Treponema pallidum of host cell surfaces.
The interaction between virulent Treponema pallidum extracted from infected rabbit testes and animal cells in culture was examined. The extent of treponemal attachment to monolayers of normal rabbit testicular and HEp-2 cells was dependent upon the incubation temperature and retained motility of the spirochetes. The specific orientation of treponemes to host cell surfaces was demonstrated by da...
متن کاملCapacity of virulent Treponema pallidum (Nichols) for deoxyribonucleic acid synthesis.
Treponema pallidum (Nichols) was extracted from infected rabbit tissue, and cell lysates were prepared for monitoring thymidine kinase and deoxyribonucleic acid polymerase activities. No thymidine kinase could be demonstrated in preparations of T. pallidum or the cultivable T. phagedenis biotype Reiter. Significant levels of deoxyribonucleic acid polymerase were detected in both treponemal samp...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1973
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.8.2.291-295.1973